This rule blocks any executable that the user tries to execute from within their, or any other user’s, profile. allow everything) followed by “%OSdrive%\Users\*” in the exceptions list on the “Exceptions” tab. This is an “Allow” rule under “Executable Rules” with a path of “*” (i.e. The main rule is to “Allow Executables Only Outside of User Profile”.
My philosophy is not to explicitly deny anything and only use “Allow” rules with exceptions due to the fact that deny rules cannot be overridden further down the line. It’s a very simple set of rules that is almost completely transparent to our users. Here’s a decent video overview of AppLocker for those who aren't familiar: After that initial process of implementing appropriate exceptions and workarounds I rarely have to touch my rules. It took about 15 minutes to setup and then it 5-30 minutes here and there for the first few weeks to troubleshoot and create exceptions for some applications.
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Even with those limitations and software that was supposed to block it the users still managed to infect them via consenting to running executables presented to them by compromised and/or malicious websites. Prior to AppLocker we had users with limited/non-admin rights and anti-virus/anti-malware software running on all machines with supposed real-time protection. This is in contrast to having to cleanup 3-5 infections per week, some of those involving a complete reimaging of the machine. Through the use of this Group Policy feature we have not had to clean up a single malware infection across 500 Windows 7 machines in over 3 years. I discovered AppLocker 3 years ago it has been a total game changer for us.
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